Variable pressure support ventilation vs. biphasic positive airway pressure/airway pressure release ventilation in experimental acute respiratory failure

Sep 16, 2026 | Government, News, Science

BMC Anesthesiol. 2026 Sep 15;26(1):564. doi: 10.1186/s12871-026-04228-6.ABSTRACTBACKGROUND: Spontaneous breathing during mechanical ventilation (MV) can improve cardiorespiratory function and lung protection. Biphasic Positive Airway Pressure (BIPAP) and Airway...

Adaptive Optics Image Analysis Using Generative AI (GPT-4) Scripting: Exploratory Study

Sep 14, 2026 | Government, News, Science

JMIR Form Res. 2026 Sep 14;10:e94906. doi: 10.2196/94906.ABSTRACTBACKGROUND: The availability of dedicated image analysis scripts for adaptive optics (AO)-flood illumination ophthalmoscopy (FIO) is limited, especially for large-scale measurements and analyses of...

Heterozygous germline mutations in MSH3, and probably MLH3, act as classical tumour suppressors, leading to excess somatic deletion mutations, signature ID4 and increased colorectal cancer risk

Sep 11, 2026 | Government, News, Science

Gut. 2026 Sep 11:gutjnl-2026-338390. doi: 10.1136/gutjnl-2026-338390. Online ahead of print.ABSTRACTBACKGROUND: MSH3 and MLH3 are non-canonical DNA mismatch repair genes, involved in repairing insertion-deletion mutations. Colorectal cancer (CRC) and adenomas have...

Retinal and choroidal morphometric analysis in fellow eye of unilateral wet age related macular degeneration using optical coherence tomography angiography

Sep 8, 2026 | Government, News, Science

BMC Ophthalmol. 2026 Sep 5;26(1):548. doi: 10.1186/s12886-026-05302-w.ABSTRACTBACKGROUND: Age-related macular degeneration (AMD) when associated with macular neovascularization can cause severe visual morbidity. This study aims to evaluate the retinal and choroidal...

In Silico Prioritization of Variants of Uncertain Significance in ABCA4 Reveals Conserved Functional Motifs

Sep 3, 2026 | Government, News, Science

Res Sq [Preprint]. 2026 Aug 25:rs.3.rs-10349982. doi: 10.21203/rs.3.rs-10349982/v1.ABSTRACTBACKGROUND: ABCA4 variants are the primary cause of Stargardt disease and also contribute to other inherited retinal disorders. Despite this central role, nearly half of all...

Epidemiology of macular dystrophy in Japan (2011-2020): a nationwide population-based study

Sep 3, 2026 | Government, News, Science

Jpn J Ophthalmol. 2026 Sep 3. doi: 10.1007/s10384-026-01410-8. Online ahead of print.ABSTRACTPURPOSE: To describe the characteristics and prevalence of macular dystrophy using a comprehensive national claims database in Japan.STUDY DESIGN: Population-based...